MRBS AS MODIFIERS OF THE RB PATHWAY AND METHODS OF USE
摘要
Human MRB genes are identified as modulators of the RB pathway, and thus are therapeutic targets for disorders associated with defective RB function. Methods for identifying modulators of RB, comprising screening for agents that modulate the activity of MRB are provided.
申请公布号
WO2004104168(A2)
申请公布日期
2004.12.02
申请号
WO2004US14964
申请日期
2004.05.13
申请人
EXELIXIS, INC.;FRANCIS-LANG, HELEN;EDGAR, KYLE, ANDREW;ADAMKEWICZ, JOANNE, I.;LICKTEIG, KIM
发明人
FRANCIS-LANG, HELEN;EDGAR, KYLE, ANDREW;ADAMKEWICZ, JOANNE, I.;LICKTEIG, KIM
