2-AMINOQUINOLINE DERIVATIVES

摘要

A 2-aminoquinoline derivative represented by the general formula [I]: wherei n R1 and R2 each represents lower alkyl, lower cycloalkyl, etc. or R1 and R2 i n combination form an aliphatic nitrogenous heterocycle in cooperation with th e nitrogen atom bonded to these; R3, R4 , R5, R6, and R7 each represents hydrogen, lower alkyl, etc.; R8 represents lower alkyl, lower alkyloxy, etc. ; and n is an integer of 0 to 4. The compound functions as a melanin- concentrating hormone receptor antagonist and is useful as a medicine for central diseases, circulatory diseases, or metabolic diseases.