发明名称 |
Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof |
摘要 |
This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention also provides a method of modifying feeding behavior of a subject which comprises administering to the subject an amount of a compound of the invention effective to decrease the consumption of food by the subject. This invention further provides a method of treating a feeding disorder in a subject which comprises administering to the subject an amount of a compound of the invention effective to decrease the consumption of food by the subject. In an embodiment of the invention, the feeding disorder is bulimia, bulimia nervosa or obesity.
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申请公布号 |
US2004242609(A1) |
申请公布日期 |
2004.12.02 |
申请号 |
US20040825643 |
申请日期 |
2004.04.15 |
申请人 |
SYNAPTIC PHARMACEUTICAL CORPORATION |
发明人 |
MARZABADI MOHAMMAD R.;WETZEL JOHN;DELEON JOHN E.;LAGU BHARAT;GLUCHOWSKI CHARLES;NOBLE STEWART;NAGARATHNAM DHANAPALAN |
分类号 |
C07C233/79;C07D211/52;C07D211/58;C07D295/073;C07D401/12;C07D401/14;C07D413/14;C07D417/06;C07D471/04;C07D471/10;C07D491/04;C07D491/10;(IPC1-7):A61K31/513;C07D239/02 |
主分类号 |
C07C233/79 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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