| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide an immunogenic composition, capable of inducing protective antibodies against Helicobacter infection, and to provide a method for preparation of the immunogenic composition by means of recombination. <P>SOLUTION: The immunogenic composition comprises: (i) at least one sub-unit of a urease structural polypeptide from Helicobacter pylori, or a fragment thereof, said fragment being recognised by antibodies reacting with Helicobacter felis urease, and/or at least one sub-unit of a urease structural polypeptide from Helicobacter felis, or a fragment thereof, said fragment being recognised by antibodies reacting with Helicobacter pylori urease, (ii) and/or Heat Shock Protein (HSP), chaperonin, from Helicobacter pylori, or a fragment of said protein. <P>COPYRIGHT: (C)2005,JPO&NCIPI |
