| 摘要 |
The present invention relates to the provision and use of pressurised metere d dose inhalers (MDIs) for the effective administration of pharmaceutical aerosol formulations. Such formulations comprise a drug, a propellant comprising one of either 1,1,1,2-tetrafluoroethane (HFA134a) or 1,1,1,2,3,3, 3- heptafluoropropane (HFA227) or a mixture thereof, a cosolvent having a highe r polarity than HFA134a or HFA227, and a surfactant in an amount at least 0.01 % by weight of said formulation. Such MDIs comprise a canister.
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