GERÄT UND VERFAHREN ZUR SICHEREN LOKALISIERUNG UND MARKIERUNG EINER HÖHLE UND VON SENTINELL-LYMPHKNOTEN

摘要

A subcutaneous cavity marking device has detectable marker(s) attached to filler(s). Independent claims are included for the following: (a) the above device where the body includes resilient biocompatible material; (b) the above device where the body includes non bioabsorbable suture material and the marker is radiopaque; (c) the above device where the marker is not bioabsorbable and the body is bioabsorbable; (d) a composition having non-toxic non-radioactive microparticles for migrating from an insertion site to a lymph node in under 3 hours. The particles are detectable non-invasively; (e) a cavity marking delivery device having a delivery device in a lumen of a cartridge. The cartridge slides on a disengaging arm; (f) a delivery device having an ejector coupled to an elongate member. The ejector disengages a marking device seated on the member; (g) delivery systems including (f); (h) kits including (a), (b), (c), (d) or (f); (i) marking a tissue cavity using devices as in (a) and (f); (j) marking a tissue cavity using a delivery device to access the cavity and then deploy a remotely detectable device; (k) delivering a marking device into a cavity using a medical instrument probe to install an outer sheath, delivering the device through the sheath and then withdrawing the sheath; (l) delivering a marking device into a cavity using a medical instrument cannula having a side window. The device is ejected through the window by advancing a shaft that remains within the cannula; (m) marking a cavity by inserting a marking device through a small opening; the device expands to mark the borders of the larger cavity; (n) locating a sentinel lymph node by injecting a composition similar to (d); (o) making a cavity marking device by rolling or folding a sheet of bioabsorbable material around a marker; (p) making a cavity marking device by cutting a filler body material to shape, making a hole partway through the material and inserting marker(s) into the hole; (q) locating a sentinel lymph node comprising: (1) injecting a non-invasively detectable, non-radioactive, migratory contrast agent into the region of a cavity or lesion; (2) allowing the contrast agent to migrate to a sentinel lymph node; and (3) identifying the sentinel lymph node by non-invasively detecting the contrast agent in the sentinel lymph node. Preferred Features: The microparticles may be carbon or silicon dioxide.