ASSAYS FOR IDENTIFYING CHOLESTEROL - LOWERING MOLECULES

摘要

The invention relates to a gene and the encoded protein involved in cholesterol lowering, and their use in diagnostics, treatment of disease, and in the identification of molecules for the treatment and prevention of disease. The present invention thus discloses methods of screening for the identification of molecules useful in the treatment of heart disease, coronary artery disease, myocardial infarct, and lipid related metabolic disorders such as the dysmetabolic syndrome, Obesity and Diabetes type II.