METHOD FOR PRODUCING INDOLE COMPOUND

摘要

PROBLEM TO BE SOLVED: To provide a method for producing an indole compound without having a substituent at the 1-, the 2- and the 3-positions of the indole ring. SOLUTION: The method for producing the compound having general formula (III) (wherein, R1, R2, R3and R4are each an H, an alkyl, an alkoxy, a dialkylamino, an alkoxycarbonyl, a carbamoyl, an alkylcarbamoyl, a dialkylcarbamoyl, a cyano, a nitro or a halogeno group) is carried out as follows. A compound having general formula (I) [wherein, R1, R2, R3and R4denote each the same meaning as described in general formula (III)] is reacted with a compound having general formula (II) (wherein, R5and R6are each an alkyl or together form a substitutable ethylene group or the like; and X is a leaving group) in a solvent such as a primary alcohol. COPYRIGHT: (C)2005,JPO&NCIPI