发明名称 COMBINATION THERAPY WITH GLATIRAMER ACETATE AND MITOXANTRONEFOR THE TREATMENT OF MULTIPLE SCLEROSIS
摘要 The subject invention provides a method of treating a subject afflicted with a form of multiple sclerosis comprising periodically administering to the subject an amount of glatiramer acetate and an amount of mitoxantrone, where in the amounts when taken together are effective to alleviate a symptom of the form of multiple sclerosis in the subject so as to thereby treat the subject . The subject invention also provides a package comprising glatiramer acetate, mitoxantrone and instructions for use of the together to alleviate a symptom of a form of multiple sclerosis in a subject. Additionally, the subject invention provides a pharmaceutical composition comprising an amount of glatiramer acetate and an amount of mitoxantrone, wherein the amounts when taken together are effective to alleviate a symptom of a form of multiple sclerosis in a subject. The subject invention further provides a pharmaceutical combination comprising separate dosage forms of an amount of glatiramer acetate and an amount of mitoxantrone, which combination is usefu l to alleviate a symptom of a form of multiple sclerosis in a subject.
申请公布号 CA2525771(A1) 申请公布日期 2004.12.02
申请号 CA20042525771 申请日期 2004.05.14
申请人 TEVA PHARMACEUTICAL INDUSTRIES LTD. 发明人 VOLLMER, TIMOTHY
分类号 A61K38/00;A61K 主分类号 A61K38/00
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