Percutaneous absorption preparations

摘要

It is intended to provide external preparations for percutaneous application and compositions therefor whereby a hardly soluble drug such as a drug having an ergoline skeleton can be effectively absorbed via the skin into the blood under circulation while avoiding side effects on the digestive system observed in case of oral administration or side effects on the central system caused by a rapid increase in the concentration in the blood and a high adhesiveness to the skin can be established. This object can be established by composition characterized by containing a copolymer having N-vinyl-2-pyrrolidone as one of its constituents and percutaneous absorption preparations characterized by having a drug-containing adhesive layer containing such a composition and a support layer.