发明名称 |
USE OF COMPOSITIONS COMPRISING AN ESTROGENIC COMPONENT FOR THE TREATMENT AND PREVENTION OF MUSCULOSKELETAL PAIN |
摘要 |
<p>The present invention relates to a method of treating or preventing musculoskeletal pain in a mammal receiving administration of an estrogen. suppressant selected from the group consisting of aromatase inhibitors, GnRH analogues, cyclo-oxygenase 2 (COX-2) inhibitors, 17beta-hydroxysteroid dehydrogenase type 1 inhibitors, progestogens, anti-estrogens and combinations thereof, said method comprising the administration of an effective amount of an estrogenic component, wherein the estrogenic component is selected from the group consisting of : substances represented by the following formula (I) in which formula R1, R2, R3, R4 independently are a hydrogen atom, a hydroxyl group or an alkoxy group with 1-5 carbon atoms; precursors capable of liberating a substance according to the aforementioned formula when used in the present method; and mixtures of one or more of the aforementioned substances and/or precursors.</p> |
申请公布号 |
WO2004103377(A1) |
申请公布日期 |
2004.12.02 |
申请号 |
WO2004NL00354 |
申请日期 |
2004.05.19 |
申请人 |
PANTARHEI BIOSCIENCE B.V.;COELINGH BENNINK, HERMAN, JAN TIJMEN;BUNSCHOTEN, EVERT, JOHANNES |
发明人 |
COELINGH BENNINK, HERMAN, JAN TIJMEN;BUNSCHOTEN, EVERT, JOHANNES |
分类号 |
A61K31/565;A61K45/06;A61P19/02;(IPC1-7):A61K31/565 |
主分类号 |
A61K31/565 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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