SYSTEM, METHOD AND COMPUTER PRODUCT FOR PREDICTING PROTEIN-PROTEIN INTERACTIONS

摘要

System, method and computer product for predicting protein-protein interactions. In this disclosure, there is at least one biological data sour ce containing biological data. A protein-protein interactions prediction module accesses the at least one biological data source and predicts interactions with a target protein having known domain and motif information. The prediction module includes a search module that searches the at least one biological data source for a set of proteins with domain and motif informati on similar to the domain and motif information of the target protein. An extraction module extracts interaction proteins from the set of proteins. A cellular location module determines whether the extracted interaction protei ns are co-located at the same cellular location as the target protein. An analysis module determines protein-protein interactions of the interaction proteins with the target protein based on interaction domains and motifs and cellular location.