COMPOSITIONS AND COMPOUNDS FOR USE AS A NICOTINE VACCINE EMPLOYING RESPONSE SELECTIVE AGONIST OF AN ANTIGEN-PRESENTING CELL RECEPTOR AS A MOLECULAR ADJUVANT
摘要
Compounds are disclosed comprising molecular adjuvants having an antigen presenting cell-targeting ligand linked to a nicotine hapten. Methods are disclosed for employing the compounds as a nicotine vaccine for treatment or prevention of nicotine addiction.
申请公布号
EP1480672(A2)
申请公布日期
2004.12.01
申请号
EP20030709186
申请日期
2003.02.20
申请人
THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA
发明人
SANDERSON, SAM, D., G.;VENNERSTROM, JONATHAN, L.;THIELE, GEOFFREY, M.;PARAMESWARAN, MANIYAN;BEVINS, RICK, A.;SRINIVASA, CHERUKU, R.