| 摘要 |
PROBLEM TO BE SOLVED: To provide an antifungal agent which is usable for various kinds of applications for inhibiting proliferation of a causative fungus for dandruff which is resident in the skin, particularly safe antifungal agent suitable for hair cosmetics effective to prevention of occurrence of dandruff. SOLUTION: The antifungal agent comprises at least one selected from macrocyclic lactones represented by general formula (1) (wherein n is an integer of 0-4; a wavy line part represents a single bond or either one place of the wavy line part represents a double bond), macrocyclic lactones represented by general formula (2) (wherein n is an integer of 0-2; R is a hydrogen atom or a methyl group; a wavy line part represents a single bond or either one place of the wavy line part represents a double bond) and epoxy compounds represented by general formula (3) (wherein R2 is a 1-5C alkyl group, a 2-5C alkenyl group or a 2-5C alkynyl group; wavy line is a cis-isomer, a trans-isomer or a mixture of the cis-isomer and the trans-isomer). COPYRIGHT: (C)2005,JPO&NCIPI
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