摘要 |
Taxane derivatives of formula (I) in which: R is trifluoromethyl, phenyl, 2-furyl, 2-thienyl; R<1 >is t-butoxycarbonyl or benzoyl; R2 is hydroxy; R3 is hydrogen or, together with R2, it forms the residue of a cyclic carbonate of formula: [I] with the proviso that when R3 is hydrogen, R is different from phenyl. Compounds of formula (I) have antitumor activity. |