发明名称 |
IMPROVEMENTS TO gammadeltaT CELL-MEDIATED THERAPY |
摘要 |
The present invention relates to compositions and methods for determining or modulating the activity of immune and/or target cells in vitro, ex vivo or in vivo. The invention more specifically relates to methods and compositions for determining sensitivity of cells to the activity of gammadeltaT cells, as well as to the use of these compositions and methods for patient screening or selection, therapy improvement, compound selection, etc. The invention also provides compositions and kits suitable for carrying out these methods. The methods may be used in any mammalian subject, preferably any human subject that may benefit from gammadeltaT cell-mediated therapy, including patients with tumors, immune or infectious diseases. |
申请公布号 |
WO2004104591(A2) |
申请公布日期 |
2004.12.02 |
申请号 |
WO2004EP05408 |
申请日期 |
2004.05.19 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE;CHAMPAGNE, ERIC;BARBARAS, RONALD;BONNEVILLE, MARC;SCOTET, EMMANUEL |
发明人 |
CHAMPAGNE, ERIC;BARBARAS, RONALD;BONNEVILLE, MARC;SCOTET, EMMANUEL |
分类号 |
C07K14/705;G01N33/50;G01N33/573 |
主分类号 |
C07K14/705 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|