摘要 |
The present invention relates to a polymer paste and a sustained release composition comprising the paste and a biologically active agent. The polymer paste comprises a biocompatible, biodegradable polymer having an inherent viscosity of about 0.12 dL/g or less and a viscosity reducing agent, wherein the biocompatible, biodegradable polymer is present in the polymer paste in at least 60% by weight and the viscosity of the paste is about 400 cP or less. The sustained release composition comprises a biologically active agent and a polymer paste comprising a biocompatible, biodegradable polymer having an inherent viscosity of about 0.12 dL/g or less and a viscosity reducing agent, wherein the biocompatible, biodegradable polymer is present in the polymer paste in at least 60% by weight and the viscosity of the sustained release composition is about 400 cP or less. In a particular embodiment, the sustained release composition is injectable. |
申请人 |
ALKERMES CONTROLLED THERAPEUTICS, INC.;TRACY, MARK, A.;PHAM, CHIEM, V.;ASGARZADEH, FIROUZ;WANG, DON, J. |
发明人 |
TRACY, MARK, A.;PHAM, CHIEM, V.;ASGARZADEH, FIROUZ;WANG, DON, J. |