发明名称 |
DOPAMINE AND AGONISTS AND ANTAGONISTS THEREOF FOR TREATMENT OF NEURODEGENERATIVE DISEASES |
摘要 |
An agent selected from: (i) dopamine; (ii) a dopamine precursor; (iii) an agonist of the dopamine receptor type 1 family (D1-R agonist); (iv) an antagonist of the dopamine receptor type 2 family (D2-R antagonist); (v) a combination of (i) and (ii); or (vi) a combination of (i), (ii) or (iii) with (iv), down-regulates the suppressive activity of CD4+CD25+ regulatory T cells (Treg) on CD4+CD25- effector T cells (Teff) and is useful in methods and compositions for treating a neurodegenerative condition, disorder or disease other than Parkinson's disease. |
申请公布号 |
WO2004103263(A2) |
申请公布日期 |
2004.12.02 |
申请号 |
WO2004IL00442 |
申请日期 |
2004.05.23 |
申请人 |
YEDA RESEARCH AND DEVELOPMENT CO. LTD.;EISENBACH-SCHWARTZ, MICHAL;KIPNIS, JONATHAN |
发明人 |
EISENBACH-SCHWARTZ, MICHAL;KIPNIS, JONATHAN |
分类号 |
A61K;A61K31/135;A61K45/06 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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