| 发明名称 |
PROCESS FOR SYNTHESIZING beta-LACTAMASE INHIBITOR INTERMEDIATES |
| 摘要 |
<p>The invention relates to an enzymatic process for the production of an intermediate, bicyclic-heteroaryl-2-carboxylic acid, of the formula (I) wherein X and Y are defined in the specification and which are useful in the preparation of beta-lactamase inhibitors, by selective enzymatic hydrolysis of a mixture of positional hydrolyzable esters of the formula (II) and (III) where X, Y and R are defined in the specification.</p> |
| 申请公布号 |
WO2004104008(A1) |
申请公布日期 |
2004.12.02 |
| 申请号 |
WO2004US14833 |
申请日期 |
2004.05.12 |
| 申请人 |
WYETH HOLDINGS CORPORATION;MATUR, RAMESH, VENKAT;RUPPEN, MARK, EDWARD |
发明人 |
MATUR, RAMESH, VENKAT;RUPPEN, MARK, EDWARD |
| 分类号 |
C07D487/04;C07D519/00;C12P17/00;C12P17/18;(IPC1-7):C07D487/04;C07D471/04;C07D513/04;C07D498/04 |
主分类号 |
C07D487/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
