| 发明名称 |
PYRROLO-ISOQUINOLINE, AZEPINO- AND DIAZEPINO-INDOLE DERIVATIVES, THEIR USE AND PHARMACEUTICAL COMPISITIONS CONTAINING THEM |
| 摘要 |
Compounds of the formula below are poly(ADP-ribosyl)transferase (PARP) inhibitors, and are useful as therapeutics in treatment of cancers and the amelioration of the effects of stroke, head trauma, and neurodegenerative disease. As cancer therapeutics, the compounds of the invention may be used, e.g., in combination with cytotoxic agents and/or radiation. |
| 申请公布号 |
HU0105414(A3) |
申请公布日期 |
2003.04.28 |
| 申请号 |
HU20010005414 |
申请日期 |
2000.01.10 |
| 申请人 |
CANCER RESEARCH TECHNOLOGY LTD., LONDON |
发明人 |
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| 分类号 |
A61K;A61K31/437;A61K31/4375;A61K31/55;A61K31/551;A61P;A61P3/10;A61P9/10;A61P25/28;A61P29/00;A61P35/00;A61P43/00;C07D;C07D209/00;C07D221/00;C07D223/00;C07D243/00;C07D471/06;C07D487/00;C07D487/06;C07D519/00 |
主分类号 |
A61K |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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