| 发明名称 |
Aminooxy functionalized oligomers, oligomer arrays and methods of using them |
| 摘要 |
The present invention provides oligomers which are specifically hybridizable with a selected sequence of RNA or DNA wherein at least one of the nucleoside moieties of the oligomer is modified to include an aminooxy linkage. These oligomers are useful for diagnostic, therapeutic and investigative purposes.
|
| 申请公布号 |
US6825331(B2) |
申请公布日期 |
2004.11.30 |
| 申请号 |
US20020234764 |
申请日期 |
2002.09.03 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
MANOHARAN MUTHIAH;LONNBERG HARRI;SALO HARRI;VIRTA PASI |
| 分类号 |
A61K31/7072;A61K31/7076;A61P43/00;C07H15/203;C07H19/04;C07H19/06;C07H19/16;C07H21/00;(IPC1-7):C07H21/00 |
主分类号 |
A61K31/7072 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
