发明名称 17alpha-fluoroalkyl-11beta-benzaldoxime steroids, process for their production, pharmaceutical preparations that contain these steroids as well as their use for the production of pharmaceutical agents
摘要 Compounds of general formula I as well as their pharmaceutically compatible salts are described, in which R1 stands for hydrogen, C1- to C6-alkyl, COR4, COOR4, COSR4 or CONHR5, in which R4 is C1- to C6-alkyl or unsubstituted or substituted aryl and in which R5 is hydrogen, C1- to C6-alkyl or unsubstituted or substituted aryl, in which R2 also stands for hydrogen, C1- to C6-alkyl or C1- to C6-acyl, and R3 stands for a CnF2n+1 group, in which n=1, 2 or 3, or a CH2O(CH2)mCnF2n+1 group, in which m=0 or 1 and n=1, 2 or 3. In addition, a process for the production of the compounds with general formula I is indicated. The compounds can be used for the production of pharmaceutical agents.
申请公布号 US6825182(B2) 申请公布日期 2004.11.30
申请号 US20030429247 申请日期 2003.05.05
申请人 SCHERING AG 发明人 RING SVEN;SCHUBERT GERD;TORNUS INGO;KAUFMANN GUENTER;ELGER WALTER;SCHNEIDER BIRGITT
分类号 A61K31/56;C07J1/00;C07J41/00;C07J75/00;(IPC1-7):A61K31/56 主分类号 A61K31/56
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