NOVO PROCESSO PARA A PRODUCAO DE ALFA-(2,4-DISSULFOFENIL)-N-TERC-BUTILNITRONA EOS SEUS SAIS FARMACEUTICAMENTE ACEITAVEIS

摘要

An integrated process for preparing alpha-(2,4-disulfophenyl)-N-tert-butylnitrone and its salts is disclosed in which N-tert-butylhydroxylamine acid addition salt is incompletely neutralised so as to leave catalytic amounts of acid and the neutralisation product is condensed with an appropriate aldehyde.