发明名称 |
Tetrahydroquinoline derivatives as antithrombotic agents |
摘要 |
This invention relates generally to tetracyclic tetrahydroquinoline compounds, and analogues thereof, and pharmaceutically acceptable salt forms thereof, which are selective inhibitors of serine protease enzymes, especially factor VIIa; pharmaceutical compositions containing the same; and methods of using the same as anticoagulant agents for modulation of the coagulation cascade.
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申请公布号 |
US6825208(B2) |
申请公布日期 |
2004.11.30 |
申请号 |
US20020223860 |
申请日期 |
2002.08.20 |
申请人 |
BRISTOL-MYERS SQUIBB PHARMA COMPANY |
发明人 |
ZHOU JINGLAN;ROBINSON LESLIE;GUBERNATOR NIKOLAUS M.;SAIAH EDDINE;BAI XU;GU XIN |
分类号 |
A61P7/04;C07D221/18;(IPC1-7):A61K31/473 |
主分类号 |
A61P7/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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