| 发明名称 |
PROCESS FOR THE PREPARATION OF (E)-5-(2-BROMOVINYL)-2'-DEOXYURIDINE |
| 摘要 |
Process of preparing (E)-5-(2-bromovynyl)-2'-deoxyuridine (Brivudine) characterized in that halogen-free solvent selected form esters or cyclic ethers are used in the bromination step of 5-ethyl-2'-deoxyuridine diacylate. The use of solvents is advantageous in respect of toxicity, discharge costs and environment protection. |
| 申请公布号 |
PL363611(A1) |
申请公布日期 |
2004.11.29 |
| 申请号 |
PL20020363611 |
申请日期 |
2002.02.21 |
| 申请人 |
MENARINI RICERCHE SPA.;BERLIN-CHEMIE AG |
发明人 |
SALIMBENI ALDO;MAGGI CARLO ALBERTO;MANZINI STEFANO;TUROZZI DAMIANO |
| 分类号 |
C07H19/073;C07B61/00;C07H19/06 |
主分类号 |
C07H19/073 |
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