发明名称 CYANO-SUBSTITUTED DIHYDROPYRIMIDINE COMPOUNDS AND THEIR USE TO TREAT DISEASES
摘要 The present invention provides compounds of formula I and pharmaceutically acceptable salts thereof. The formula I compounds induce mitotic arrest thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases which can be treated by inducing mitotic arrest.
申请公布号 PL364005(A1) 申请公布日期 2004.11.29
申请号 PL20020364005 申请日期 2002.03.26
申请人 BRISTOL-MYERS SQUIBB CO. 发明人 LOMBARDO LOUIS J.;WU LAURENCE I.
分类号 C07D239/42;A61K31/505;A61K31/506;A61K31/513;A61K45/00;A61P1/04;A61P1/16;A61P9/00;A61P9/06;A61P9/10;A61P9/14;A61P13/12;A61P17/06;A61P19/00;A61P19/02;A61P21/00;A61P21/04;A61P25/14;A61P25/16;A61P25/28;A61P27/16;A61P29/00;A61P35/00;A61P35/02;A61P37/06;C07D211/90;C07D239/22;C07D401/04;C07D401/10;C07D403/10;C07D403/12;C07D405/04;C07D409/04;C07D409/06;C07D409/10;C07D409/12;C07D413/04;C07D413/10;C07D417/04 主分类号 C07D239/42
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