摘要 |
A method of treating or preventing a condition selected from the group consisting of migraine, inflammatory diseases, stroke, acute and chronic pain, hypovolemic shock, traumatic shock, reperfusion injury, Crohn's disease, ulcerative colitis, septic shock, multiple sclerosis, AIDS associated dementia, neurodegenerative diseases, neuron toxicity, Alzheimer's disease, chemical dependencies and addictions, emesis, epilepsy, anxiety, psychosis, head trauma, adult respiratory distress syndrome (ARDS), morphing induced tolerance and withdrawal symptoms, inflammatory bowel disease, osteoarthritis, rheumatoid arthritis, ovulation, dilated cardiomyopathy, acute spinal cord injury, Huntington's disease, Parkinson's disease, glaucoma, macular degeneration, diabetic neuropathy, diabetic nephropathy and cancer in a non-human mammal, comprising administering to the mammal an effective amount of a compound according to Formula I; a method of inhibiting NOS in a non-human mammal comprising administering to the mammal a NOS inhibiting effective amound of a compound according to Formula I; and the use off a compound according to Formula I in the manufacture of a medicament for treating or preventing a condition selected from the group described above. (62) Divided out of 326874
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