| 摘要 |
A pharmaceutical composition for parenteral administration comprises dronedarone, a physiologically acceptable buffer solution capable of maintaining the pH of the composition between 3 and 5 and a physiologically acceptable water-soluble b-cyclodextrin derivative. Preferably the buffer solution is a system chosen from acetic acid/alkali metal acetate, fumaric acid/ alkali metal fumarate, succinic acid/alkali metal succinate, citric acid/alkali metal citrate, tartaric acid/alkali metal tartrate, lactic acid/alkali metal lactate, maleic acid/ alkali metal maleate, methansulphonic acid/ alkali metal methanesulphonate or monoalkali metal phosphate.
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