CONTROLLED DRUG DELIVERY SYSTEM OF LOCALLY IMPLANTABLE AGENT CAPABLE OF CONTROLLING INITIAL RELEASE SPEED AND DURATION BY USING MONOMERS OF A BIODEGRADABLE POLYMER TO REDUCE TOXICITY DUE TO DRUG-OVERADMINISTRATION AND OTHER ADVERSE SIDE EFFECTS

摘要

PURPOSE: Provided is a controlled drug delivery system of a locally implantable agent which controls an initial release speed and duration of drug by adding a biodegradable polymer as a carrier and its monomers to reduce toxicity due to drug-overadministration and other adverse side effects. CONSTITUTION: The controlled drug delivery system of a locally implantable agent is characterized by including or dispersing an effective amount of drug in a mixture of 20-99 wt.% of a biodegradable polymer as a carrier and 1-80 wt.% of its monomers.