摘要 |
Disclosed are compounds of formula (I), wherein: X is selected from CH, C(C1-6alkyl) and N, m is 0 or 1, L1 is C1-6alkyl, Y1 is selected from C(O) and C(S), Y2 is selected from CH2, C(O), C(S) and SO2, R1 and R2 are independently selected from H or optionally substituted alkyl, aryl, aralkyl, cycloalkyl, cycloalkyl-alkyl, heteroaryl, heteroaryl-alkyl, heterocycloalkyl and heterocycloalkyl-alkyl, and the remaining substituents are defined herein. The compounds are used for the manufacture of medicaments for the treatment of nervous system disorders.
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申请人 |
ORTHO-MCNEIL PHARMACEUTICAL, INC |
发明人 |
KORDIK, CHERYL P;REITZ, ALLEN B;COATS, STEVEN J;LUO, CHI;PAN, KEVIN;PARKER, MICHAEL H |