发明名称 Amidoalkyl-piperidine and amidoalkyl-piperazine derivatives for treating of nervous system disorders
摘要 Disclosed are compounds of formula (I), wherein: X is selected from CH, C(C1-6alkyl) and N, m is 0 or 1, L1 is C1-6alkyl, Y1 is selected from C(O) and C(S), Y2 is selected from CH2, C(O), C(S) and SO2, R1 and R2 are independently selected from H or optionally substituted alkyl, aryl, aralkyl, cycloalkyl, cycloalkyl-alkyl, heteroaryl, heteroaryl-alkyl, heterocycloalkyl and heterocycloalkyl-alkyl, and the remaining substituents are defined herein. The compounds are used for the manufacture of medicaments for the treatment of nervous system disorders.
申请公布号 NZ525547(A) 申请公布日期 2004.11.26
申请号 NZ20010525547 申请日期 2001.10.23
申请人 ORTHO-MCNEIL PHARMACEUTICAL, INC 发明人 KORDIK, CHERYL P;REITZ, ALLEN B;COATS, STEVEN J;LUO, CHI;PAN, KEVIN;PARKER, MICHAEL H
分类号 C07D295/18;A61K31/445;A61K31/4525;A61K31/4535;A61K31/454;A61K31/4545;A61K31/4709;A61K31/495;A61K31/496;A61K31/5377;A61P1/08;A61P17/04;A61P25/00;A61P25/06;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P29/00;C07D211/16;C07D211/34;C07D213/44;C07D213/56;C07D213/75;C07D295/192;C07D307/46;C07D307/68;C07D401/10;C07D401/12;C07D401/14;C07D405/10;C07D405/12;C07D409/10;C07D409/12;C07D413/06;C07D413/14;(IPC1-7):C07D211/16 主分类号 C07D295/18
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