(3R, 4R)-delta8-tetrahydrocannabinol-11-oic acids useful for decreasing cell proliferation

摘要

Use of a compound of formula (I) wherein, R1 is hydrogen, -COCH3, or -COCH2CH3; R2 is a branched C5-12 alkyl compound which may have a terminal aromatic ring, or a branched -OCHCH3(CH2)m alkyl compound which may have a terminal aromatic ring, wherein m is 0 to 7; R3 is hydrogen, a C1-8 alkyl compound, or a C1-8 alkanol compound; and Y is nil or a bridging group of NH or oxygen; provided that where Y is oxygen and R2 is a branched C5-12 alkyl compound, R3 is not -CHCH3, for the manufacture of a medicament for decreasing cell proliferation in a mammal.