| 摘要 |
Producing dedifferentiated, programmable stem cells of human monocytic origin, comprises isolating monocytes from human blood, propagating the monocytes in a culture medium which contains the cellular growth factor M-CSF, cultivating the monocytes, subsequently or simultaneously, in a culture medium containing IL-3 and obtaining the human adult dedifferentiated programmable stem cells by separating the cells from the culture medium. Independent claims are also included for: (1) dedifferentiated, programmable stem cells of human monocytic origin; (2) a pharmaceutical composition containing the dedifferentiated, programmable stem cells of (1); (3) differentiated, isolated, somatic target cells and/or target tissue, obtained by reprogramming the stem cells of (1), comprising the membrane-associated surface antigen CD14; and (4) implantable materials coated with the dedifferentiated, programmable stem cells of (1) or the somatic target cells and/or target tissue of (3).
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