发明名称 5-membered heterocycles, preparation and application thereof as medicaments
摘要 Thiazole and imidazole derivatives are described. The compounds can be used in pharmaceutical compositions for inhibiting monoamine oxidases (MAO), particularly MAO B, inhibiting lipidic peroxidation, modulating activity via sodium channels and for treating Parkinson's disease, senile dementia, Alzheimer's disease, Huntington's, amyotrophic lateral sclerosis, schizophrenia, depression, psychoses, migraine and pain, particularly neuropathic pain.
申请公布号 NZ528645(A) 申请公布日期 2004.11.26
申请号 NZ20020528645 申请日期 2002.04.09
申请人 SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S 发明人 HARNETT, JEREMIAH;BIGG, DENNIS;LIBERATORE, ANNE-MARIE;ROLLAND, ALAIN
分类号 C07D233/64;A61K31/33;A61K31/416;A61K31/417;A61K31/421;A61K31/426;A61K31/454;A61K31/497;A61K31/5377;A61K31/538;A61K31/541;A61K31/5415;A61K31/551;A61P25/00;A61P25/04;A61P25/06;A61P25/14;A61P25/16;A61P25/18;A61P25/24;A61P25/28;A61P43/00;C07D233/50;C07D233/54;C07D263/32;C07D277/20;C07D277/28;C07D277/30;C07D277/34;C07D401/06;C07D403/10;C07D417/04;C07D417/06;C07D417/14;(IPC1-7):C07D277/28;A61P29/00 主分类号 C07D233/64
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