| 摘要 |
The present invention relates to sulfur-containing naphthoylimide derivatives, the preparation and the use thereof. By expanding the conjugate plane of the naphthoylimide with condensed 5- or 6-member aromatic heterocyclic ring and / or introducing a sulfur atom, the antineoplastic activity of the compounds is improved. For inhibition of the proliferation of tumor-cells from different origins, such as lung cancer, carcinoma ventriculi, liver cancer and leucaemia in human beings, the compounds show remarkable effects with clear quantity-effect relationships. |
| 申请人 |
EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY;SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCE;DALIAN UNIVERSITY OF TECHNOLOGY;QIAN, XUHONG;LI, YONGGANG;XU, YUFANG;DING, JIAN;LIN, LIPING;MIAO, ZEHONG;ZHU, HONG;QU, BAOYUAN |
发明人 |
QIAN, XUHONG;LI, YONGGANG;XU, YUFANG;DING, JIAN;LIN, LIPING;MIAO, ZEHONG;ZHU, HONG;QU, BAOYUAN |
