BIOREACTOR FOR PRODUCING A TISSUE PROSTHESIS, PARTICULARLY A HEART VALVE

摘要

The invention relates to a bioreactor for producing a tissue prosthesis, particularly a heart valve, comprising a reactor chamber for holding a fluid nutrient medium and a prosthesis support, a device for placing the prosthesis support in the area of the reaction chamber, and a drive device for generating a pulsation flow of the nutrient medium inside the reactor chamber. The bioreactor is characterized in that an exciter device is provided for generating a frequency excitation of the nutrient medium and/or of the prosthesis support, said frequency excitation superimposing the pulsation flow of the nutrient medium. The invention also relates to a method for operating a bioreactor.