发明名称 Ophthalmic compositions for treating ocular hypertension
摘要 Disclosed is a compound of the structural formula I wherein the substituents are as described in the specification. Compounds of the structure disclosed are useful in the treatment of ocular hypertension, glaucoma, macular edema, macular degeneration, increasing retinal and optic nerve head blood velocity, increasing retinal and optic nerve oxygen tension, preventing hyperpolarisation of a mammalian cell containing a potassium channel, treating Alzhemer's disease, depression, cognitive disorders and arrhythmia disorders.
申请公布号 NZ539593(A) 申请公布日期 2006.12.22
申请号 NZ20030539593 申请日期 2003.11.04
申请人 MERCK & CO 发明人 DOHERTY, JAMES B;CHEN, MENG-HSIN;LIU, LUPING;NATARAJAN, SWAMINATHAN R;TYNERBOR, ROBERT M
分类号 A61K31/416;A61P27/06;C07D231/56;C07F9/6503;(IPC1-7):C07D231/56 主分类号 A61K31/416
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