PROCESS FOR PREPARING OMEGA-ANHYDROUS GATIFLOXACIN

摘要

Novel process to manufacture omega form and form-II of anhydrous Gatifloxaci n (1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-l~piperazinyl)-3- guinodine carboxylic acid) having structural formula (I) is disclosed. The invention does not require high temperature or use of column chromatography for purification. Moreover the solvents being used in the process can be recovered and recycled. These factors make the process industrially efficien t.