| 摘要 |
Pumping cartridges useful for medical and surgical pumping and infusion procedures are disclosed. Methods for manufacturing and utilizing such pumping cartridges and methods for pumping or infusing liquids for delivery to the body of a patient or a surgical or medical instrument for performing a medical treatment are also described. The invention includes, in one aspect, a series of pumping cartridges comprising cylinders and pistons constructed and arranged for sliding or reciprocating motion within the cylinders. The pistons and/or cylinders can comprise a sealing component including a circumferential, flared sealing flange and can be configured to enable the pumping cartridge to generate high liquid pumping pressures, for example above 1,000 psig. Many of the pumping cartridges disclosed can be relatively easily manufactured at a low cost per unit and can be configured to be detachable from a pump drive unit and disposable after a single use. Various compact flow path configurations are provided in the several pumping cartridge embodiments described, including a Y-shaped configuration, a T-shaped configuration, and an axial configuration. Some pumping cartridges disclosed include pistons including or at least partially forming a valve and/or pistons that are relatively movable with respect to a piston rod to which they are connected. Valve including a valve seat and a movable sealing element able to create a seal capable of withstanding differences in fluid pressures thereacross of at least about 1,000 psi, and in some cases up to in excess of 10,000 psi, without substantial fluid leakage therethrough are disclosed. In some of the disclosed valves, the movable sealing element is concave in shape, and can be curved, to create a mechanical advantage for improved sealing performance. Methods for manufacturing axially-configured pumping cartridges from thin-walled tubing are also disclosed, as well as a series of methods for pumping or infusing a liquid for delivery to the body of a patient or a surgical or medical instrument for performing a medical treatment using the above-mentioned pumping cartridges and devices.
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