METHOD AND COMPOSITION FOR PREPARING A COMPOUND USING A BENZOLATING AGENT ESSENTIALLY FREE OF RING CHLORINATION

摘要

This invention relates to methods and compositions for preparing compounds using a benzoylating agent essentially free of ring chlorination. In one alternative embodiment, the present invention relates to methods and compositions for preparing taxanes essentially free of ring chlorinated impurities. In another alternative embodiment, the present invention comprises methods for converting taxane amine to paclitaxel by contacting the taxane amine with a benzoylating agent essentially free of ring chlorination.