<p>It is clarified that apoptosis is induced and thus cell proliferation is inhibited in various cancer cells by inhibiting the expression of genes WRN, BLM and RecQ1 belonging to the RecQ helicase family. It is considered that a compound inhibiting the expression of a gene of the RecQ helicase family or the function of a RecQ helicase protein has an effect of inducing apoptosis.</p>
申请公布号
WO2004100990(A1)
申请公布日期
2004.11.25
申请号
WO2004JP07145
申请日期
2004.05.19
申请人
GENECARE RESEARCH INSTITUTE CO., LTD.;TAKAGI, MOTOKI;SHIMAMOTO, AKIRA;FURUICHI, YASUHIRO;SATO, AYUMI