| 发明名称 |
CYTOTOXIC INDENO AND ISOINDOLOISOQUINOLONES |
| 摘要 |
The synthesis and biological activity of benzoisoindoloisoquinolone compound s are described. The synthesis and biological activity of C-11-substituted indenoisoquinolones are also described. Indenoisoquinolones substituted at C - 11 are prepared by McMurry reactions of 11-ketoindenoisoquinolones with aldehydes.
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| 申请公布号 |
CA2525099(A1) |
申请公布日期 |
2004.11.25 |
| 申请号 |
CA20042525099 |
申请日期 |
2004.05.11 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE DEP ART;PURDUE RESEARCH FOUNDATION |
发明人 |
POMMIER, YVES G.;CUSHMAN, MARK S. |
| 分类号 |
A61K31/473;A61K;A61K31/4745;C07D221/18;C07D471/12;C07D491/02;C07D491/04 |
主分类号 |
A61K31/473 |
| 代理机构 |
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代理人 |
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