发明名称 |
Compositions and methods for labeling oligonucleotides |
摘要 |
A novel method for the labeling of oligonucleotides which results in the economical synthesis of 5' labeled molecules. A set of suitably protected and carefully selected set of amino linkers, a modified deprotination/cleavage protocol and standard coupling methodologies to are used to allow for the convergent synthesis of any number of labeled oligonucleotides.
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申请公布号 |
US2004234957(A9) |
申请公布日期 |
2004.11.25 |
申请号 |
US20010894423 |
申请日期 |
2001.06.28 |
申请人 |
SYNGEN, INC. |
发明人 |
CHIARELLO RONALD H.;LIU WING-CHEONG;ALVARADO GABRIEL G. |
分类号 |
C07D311/80;C07D405/12;C07D491/22;C07H21/04;C12N;(IPC1-7):C12Q1/68 |
主分类号 |
C07D311/80 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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