| 摘要 |
The present invention provides biomolecules and the use of these biomolecule s for the differential diagnosis of a breast cancer and/or a non-malignant disease of the breast. In particular the present invention provides methods for detecting biomolecules within a test sample as well as a database comprising of mass profiles of biomolecules specific for healthy subjects, subjects having a precancerous lesion of the breast, subjects having a breas t cancer or a metastasised breast cancer or subjects having a non-malignant disease of the breast. Furthermore, the present invention provides methods f or the characterization of said biomolecules using gas phase ion spectrometry. In addition, the present invention provides methods for the identification of said biomolecules provided that they are proteins or polypeptides. The invention further provides kits for the differential diagnosis of a non- malignant disease of the breast or breast cancer. |
