发明名称 |
DETECTION OF BIOCHEMICAL INTERACTIONS ON A BIOSENSOR USING TUNABLE FILTERS AND TUNABLE LASERS |
摘要 |
An apparatus and method for detection of peak wavelength values of colorimetric resonant optical biosensors using tunable filters and tunable lasers is provided. Biomolecular interactions may be detected on a biosensor by directing collimated white light towards a surface of the biosensor. Molecular binding on the surface of the biosensor is indicated by a shift in the peak wavelength value of reflected or transmitted light from the biosensor, while an increase in the wavelength corresponds to an increase in molecular absorption. A tunable laser light source may generate the collimat ed white light and a tunable filter may receive the reflected or transmitted light and pass the light to a photodiode sensor. The photodiode sensor then quantifies an amount of the light reflected or transmitted through the tunab le filter as a function of the tuning voltage of the tunable filter.
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申请公布号 |
CA2525240(A1) |
申请公布日期 |
2004.11.25 |
申请号 |
CA20042525240 |
申请日期 |
2004.05.07 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;SRU BIOSYSTEMS, INC. |
发明人 |
MATEUS, CARLOS;CUNNINGHAM, BRIAN T.;CHANG-HASNAIN, CONSTANCE;LI, PETER Y |
分类号 |
G01N33/50;G01N21/00;G01N21/39;G01N21/45;G01N21/75;G01N33/53;G01N33/543 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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