摘要 |
An external patch capable of stable prolonged release and transdermal absorption of active ingredient hormones (estrogens and/or progestogens) contained in a pressure sensitive adhesive layer, which external patch ensur es low irritation on the skin. In particular, an external patch comprising a support and, superimposed thereon, a pressure sensitive adhesive layer, characterized in that the pressure sensitive adhesive layer comprises, as indispensable components, 5 to 50 wt.% of styrene/isoprene/styrene block copolymer, 20 to 70 wt.% of tackifier resin, 10 to 60 wt.% of softener and 1 to 20 wt.% of polyvinylpyrrolidone and contains, as an active ingredient, estrogen and/or progestogen.
|
申请人 |
FUSO PHARMACEUTICAL INDUSTRIES, LTD.;TEIKOKU SEIYAKU CO., LTD. |
发明人 |
YAMAJI, MASAHIRO;HATTORI, KENICHI;MATSUSHITA, KUNIHIKO |