| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide an implant made from a titanium, the surface of which is early modified to simply and exactly realize to obtain a synostosis instead of the conventional surface modification of the implant made from the titanium in which its treatment has been complicated and unstable and to provide a method for surface treating the same. <P>SOLUTION: The surface of the implant made from the titanium is coated with a phosphorylated amino acid (phosphorylated tyrosine, phosphorylated serine, and phosphorylated threonine are preferred) and/or phosphorylated peptide (that in which phosphorylation of the terminal group of peptide arranged in order of arginine-glycine-aspartic acid has been performed is preferred). The coating treatment of the surface of the implant made from the titanium is preferred to be performed after the surface is cleaned by at least one type of an aqueous solution selected from the group consisting of the aqueous solution of sodium peroxodisulfate (Na<SB>2</SB>S<SB>2</SB>O<SB>8</SB>), the concentration of which is 0.05-5 wt%, the aqueous solution of sulfuric acid (H<SB>2</SB>SO<SB>4</SB>), the normality of which is 0.01 N or more, and the aqueous solution of hydrochloric acid (HCl), the normality of which is 0.01 N or more. <P>COPYRIGHT: (C)2005,JPO&NCIPI |
