发明名称 |
PEPTIDE SPEZIFISCH FÜR ANTIKÖRPER GEGEN PEPTIDCONCENSUSSEQUENZEN AUS DER CS4-CFA/IPRPTEINFAMILIE |
摘要 |
This invention relates to amino acid sequences from within a consensus peptide of the formula: VEKNITVTASVDPTIDLLQADGSALPSAVALTYSPA (Seq. #1). Eight mer peptides from within the consensus peptide were tested against an antibody raised to the consensus peptide. Studies relating to antibody raised to denatured proteins from the natural organisms producing the family of proteins were also useful and showed particular value of some sequences. A sequence of the formula ASVDPTIDLLQA (Seq. #2) was identified thereby. An enlarged sequence of the formula TVTASVDPTIDLLQAD (Seq. #3) is also especially interesting as are intermediate sequences such as sequences VTASVDPTIDLLQAD (Seq. #4), TASVDPTIDLLQAD (Seq. #5), and TASVDPTIDLLQA (Seq. #6) as being binding sites for antibodies raised to the denatured proteins. |
申请公布号 |
DE69731312(D1) |
申请公布日期 |
2004.11.25 |
申请号 |
DE1997631312 |
申请日期 |
1997.08.01 |
申请人 |
DEPARTMENT OF THE ARMY, U.S. GOVERNMENT U.S. ARMY MEDICAL RESEARCH & MATERIEL COMMAND |
发明人 |
CASSELS, FREDERICK;LOOMIS-PRICE, LAWRANCE |
分类号 |
G01N33/53;A61K38/00;A61K38/08;A61K38/10;A61K39/00;A61K39/39;A61K39/395;A61P31/04;C07K2/00;C07K4/00;C07K7/00;C07K7/08;C07K14/245;C07K16/00;C07K16/12;C12N1/00;C12P21/08;(IPC1-7):A61K38/08 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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