| 摘要 |
A method of measuring the binding of an analyte molecule (4), for example biopolymer molecules, to a probe substance (3) comprises the steps of providing a probe substance (3) which is immobilized in spatial proximity to a circuit surface(1), forming a complex comprising the probe substance, the analyte molecule and an electrically conductive nanoparticle(7), wherein the nanoparticle acts electrically on a circuit of the circuit surface by current generation and/or by a change in capacitance, and detecting an electrical change in the circuit to measure the binding of the analyte molecule (4) to the probe molecule (3). |
