发明名称 |
Sphingolipid ceramide N-deacylase, methods for producing sphingolipids and sphingolipid derivatives, and sphingolipid ceramide N-deacylase gene |
摘要 |
The present invention relates to a novel sphingolipid ceramide N-deacylase (SCDase) having a wide substrate specificity; a method for enzymatically producing a lysosphingolipid or a sphingolipid derivative using the SCDase which is useful in the fields of medicine, carbohydrate engineering, cell engineering, and the like; the lysosphingolipid or sphingolipid derivative obtained by this production method; a gene which encodes a polypeptide having an SCDase activity useful in sphingolipid technology; a method for industrially producing a polypeptide having an SCDase deacylase activity and a recombinant polypeptide thereof using a transformant to which the gene is introduced; a probe or primer which hybridizes to the gene; and an antibody or a fragment thereof which specifically binds to the polypeptide.
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申请公布号 |
US6821761(B2) |
申请公布日期 |
2004.11.23 |
申请号 |
US20020150068 |
申请日期 |
2002.05.20 |
申请人 |
TAKARA BIO, INC. |
发明人 |
ITO MAKOTO;KURITA TOYOHISA;KITA KATSUHIRO;SUEYOSHI NORIYUKI;MITSUTAKE SUSUMU;FUJITA MASANORI;OKINO NOZOMU;IZU HIROYUKI;KATO IKUNOSHIN |
分类号 |
C07F9/10;C07H15/04;C07H15/10;C12N9/80;C12P13/00;C12P13/02;C12P19/26;(IPC1-7):C12P13/00 |
主分类号 |
C07F9/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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