摘要 |
<p>This invention relates to compounds of Formula I, a stereoisomer thereof, a pharmaceutically acceptable salt thereof, a prodrug thereof, or a pharmaceutically acceptable salt of a prodrug thereof. The compounds interact with CRF1 receptors, including human CRF1 receptors. This invention also relates to methods of using the compounds of the invention to treat a disorder or condition, the treatment of which can be effected or facilitated by antagonizing a CRF receptor, such as CNS disorders or diseases, particularly anxiety-related disorders such as anxiety, and mood disorders such as major depression.</p> |
申请人 |
PHARMACIA & UPJOHN COMPANY;CORBETT, JEFFREY, WAYNE;ENNIS, MICHAEL, DALTON;FRANK, KRISTINE, ELISABETH;FU, JIAN-MIN;HOFFMAN, ROBERT, LOUIS;VERHOEST, PATRICK, ROBERT |
发明人 |
CORBETT, JEFFREY, WAYNE;ENNIS, MICHAEL, DALTON;FRANK, KRISTINE, ELISABETH;FU, JIAN-MIN;HOFFMAN, ROBERT, LOUIS;VERHOEST, PATRICK, ROBERT |